Treatments
Overview
Weight loss
Clinics
Overview
London locations
Treatments
Overview
Clinics
Overview
Rated 4.8 · Verified patient reviews
UK-registered pharmacy, dispensed in the UK
Prescribed only after a clinician review
Free weekday next-day delivery in discreet packaging
OVERVIEW
Foundayo is a prescription tablet for weight management. Its active ingredient, orforglipron, works on the same appetite hormone as the well-known weekly injections, so it steadies hunger rather than burning fat.
The difference is chemistry. Most of these medicines are peptides, which the stomach breaks down, so they either have to be injected or taken under strict fasted conditions. Orforglipron is not a peptide, so it survives the stomach on its own.
In practice that means one tablet a day, at whatever time suits you, with or without food, with any drink you like. There is nothing else to remember.
Honest comparison
A tablet does not shift as much weight as the strongest pen. Here is the real gap, and who each option tends to suit.
72 weeks · Fewest rules of any option: no needle, no fasting window, no fridge.
64 weeks · More weight loss, but a fasted morning and a 30-minute wait every day.
68 weeks · One injection a week and nothing to think about in between.
72 weeks · The largest average loss, if you are happy with a weekly injection.
Separate trials, separate groups of people, so these figures sit side by side rather than head to head. Averages only, and individual results vary.
YOUR PROJECTION
Put in your details to see a personalised trajectory over 72 weeks, based on Foundayo trial outcomes.
Your BMI and estimated 72-week trajectory will appear here.
Estimate only, based on published Foundayo trial outcomes. Individual results vary.DOSING
6 strengths, one step at a time. From £120 a month, everything included.
Month 1
£120
a month
Month 2
£145
a month
Month 3
£175
a month
Month 4
£195
a month
Month 5
£225
a month
Month 6 onwards
£245
a month
THE PRACTICAL DIFFERENCE
Both are daily tablets. Only one asks you to plan your morning around it. Tap between them.
Foundayo
The other daily tablet
Orforglipron
A routine you can keep is a routine that works.
One pathway
Slows stomach emptying, helping you feel fuller for longer
Reduces appetite and the drive to eat between meals
Helps quiet the background thinking about food
Helps control the rise in blood sugar after eating
HOW IT WORKS
Clinician-led treatment works with the body’s own appetite signals rather than against them, which is why the weight tends to stay off while you are on it.
The pull towards food between meals eases, so choices get easier.
Your stomach empties more slowly, so smaller meals still satisfy.
The constant background thinking about food tends to settle.
Fewer energy dips through the day, which means fewer hunger spikes.
Two daily tablets, two very different routines. The medicine matters less than the routine you will keep.
Orforglipron · daily tablet
Any time, with or without food
Oral semaglutide · daily tablet
Fasted, then a 30-minute wait
How often
Once a day
Once a day
Food rules
None, with or without food
Empty stomach, eight hours fasted
What you drink with it
Any drink, any amount
Up to half a glass of plain water
Waiting
None
At least 30 minutes before food
Time of day
Whenever suits you
Best first thing after waking
Average trial loss
12.4% over 72 weeks
16.6% over 64 weeks
SAFETY
Side effects are common when you start any new medicine. Most are mild and ease off as your body settles, and going up more slowly helps more than anything else.
Like all medicines, orforglipron has side effects. In the ATTAIN trials the common ones were nausea, diarrhoea, constipation and being sick. They were usually mild, worst in the first week after a dose increase, and faded within a few days as the body settled.
THE MOST COMMON FOUNDAYO SIDE EFFECTS INCLUDE
These are usually worst in the first week after a dose increase and settle within a few days. Going up more slowly helps more than anything else.
WE WILL NOT PRESCRIBE IT IF
Rare but serious — get medical help straight away for severe tummy pain spreading to your back, yellow skin or eyes, swelling of the face, lips or throat, trouble breathing, or vomiting you cannot stop.
Climb the doses slowly, use smaller plates, stop when comfortable rather than full, keep fatty and fried food light for a few days after a step up, and drink steadily. Most sickness and gut upset fades within a week.
Constipation, reflux, bloating, dizziness and tiredness can also happen. Speak to the clinical team if a symptom is lasting, worsening, or getting in the way of your usual routine.
Message the clinical team on WhatsApp, seven days a week. We can tell you what needs attention and what usually settles on its own.
MESSAGE YOUR CLINICAL TEAM
Cancel anytime · No lock-in · No consultation fee
QUESTIONS
In the ATTAIN-1 trial, adults taking the highest strength lost an average of 12.4% of their body weight over 72 weeks. Individual results vary.
The strongest injection has a higher average trial result, while Foundayo is a tablet with no needles, fasting rules or fridge requirements.
Appetite changes can appear in the first few weeks. Weight loss usually becomes clearer from the third month.
Foundayo is prescription-only and should be prescribed and monitored by a registered clinician.
The most common are nausea, diarrhoea, constipation, vomiting and indigestion.
Take one tablet once a day, whenever suits you, with or without food.
Take it as soon as you remember unless the next dose is due within about eight hours. Never take two in one day.
No. Store tablets at room temperature below 30 degrees, away from damp.
Prices on this page start at £120 per month and include clinician review, tablets, delivery and ongoing support.
Authored by · 26 August 2026
Prescribing pharmacist
GPhC 2212755
Reviewed by · 26 August 2026
Clinical pharmacist, medical review
UK-registered healthcare professional
★★★★★
from 1 verified review
Prescription, clinician review and pharmacy delivery included. You only pay if our clinicians approve your treatment.
✓ No charge unless our clinicians approve your treatment
Foundayo · 0.8mg · from £120/mo
from £120 a month
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WEIGHT LOSS
LONDON LOCATIONS
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